منابع مشابه
Enzymic formation of D-malate.
Tubbs & Greville (1961) showed that D-2hydroxy acid dehydrogenase (EC 1.1.2.4), present in liver and kidney in several animal species, catalyses the oxidation of D-lactate, D-malate and various straight-chain homologues. Similar NADindependent D-lactate dehydrogenases have been isolated from micro-organisms (Haugaard, 1959; de Ley & Schel, 1959; Snoswell, 1959; Nygaard, 1960). However, the meta...
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Incubation of 6-phosphogluconate dehydrogenase from Candida utilis with either acetyl phosphate, 1,3-diphosphoglycerate or carbamoyl phosphate results in the phosphorylation of the protein. The binding of one phosphate residue per enzyme subunit does not affect significantly the kinetic properties, but makes the enzyme less reactive toward thiol reagents, trypsin and pyridoxal 5'-phosphate. We ...
متن کاملGlycation (non-enzymic glycosylation) inactivates glutathione reductase.
Non-enzymic binding of sugars to proteins (glycation) is a common biological phenomenon that is increased in diabetes. Most work has been directed towards structural proteins which may be present for many years and would continue to accumulate sugar residues. As glycation is a non-specific reaction, other proteins such as enzymes will also be susceptible to glycation and could well display alte...
متن کاملEnzymic formation of oestrone 3-glucuronide by rabbit-liver microsomes.
1. A method for the subcellular fractionation of intestinal mucosa is described. The subcellular fractions were characterized by electron microscopy and by deternining the distributions of cytochrome oxidase and alkaline phosphatase in the subcellular fractions. 2. The subcellular distribution of peptidases hydrolysing L-leucylglycine and glycylglycine has been determined in intestinal mucosa. ...
متن کاملEnzymic formation of p-hydroxybenzoate from p-hydroxycinnamate.
An enzyme that converts p-hydroxycinnamate into p-hydroxybenzoate was found in rat liver. It is localized in the mitochondria and requires ATP. The activity is lost when the mitochondria are stored frozen overnight. Addition of magnesium chloride, cytochrome c, GSH, coenzyme A or potassium cyanide did not have any effect on the activity. When the rats were fed with alpha-p-chlorophenoxyisobutyr...
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ژورنال
عنوان ژورنال: Nature
سال: 1958
ISSN: 0028-0836,1476-4687
DOI: 10.1038/182313a0